Our Research
The major goal of the lab is to understand how the domain organization of the ER and nuclear envelope is established and maintained to regulate cellular functions. An understanding will provide insight into how distinct membrane domains with specific protein and lipid identities are formed to impart specialized functions.
Our current areas of research include:
(1) Lipid-mediated regulation that shapes nuclear envelope and ER identity.
(2) Regulation of diffusional exchange within the ER and nuclear envelope membrane network.
(3) Nuclear envelope and ER dynamics during mitosis.
(4) Identifying functions for previously uncharacterized nuclear envelope-associated proteins and pathways.
[more soon!]
